Tired, Low Mood & Forgetful? It May Be Time To Check Your Vitamin B12 Levels

Vitamin B12 is vital for energy, a healthy nervous system and regulating mood. Deficiencies have been shown to occur in around 6% of those under 60 and 20% of those over the age of 60 [1].

However, there are a growing number of UK clinics marketing vitamin B12 injections coming with health claims such as ‘weight loss’, ‘hangover cure’, and ‘popular with celebs'. 

The big question is whether we really need them…

Vitamin B12 is known as the energy vitamin and plays a role in converting the food we eat into energy within the body. B12 also plays an important role with the formation of healthy red blood cells and maintaining the function of the nervous system.

The UK government currently recommends that adults 19-64 years of age consume 1.5 (mcg) per day. This can be fulfilled from dietary sources such as meat, fish, eggs and dairy products.

Despite this, a recent study concluded that 1 in 12 women between 19-39 were deficient in B12 despite consuming at least the UK recommended minimum intake. The study concluded that levels should be measured in women pre-conceptionally or in early pregnancy to avoid potential deficiencies [2].

The reference nutrient intake for B12 is currently higher in the US and Europe.

Symptoms can vary from extreme tiredness, a general lack of energy, pins and needles, a sore or red tongue, mouth ulcers, disturbed vision, loss of memory or forgetfulness and some psychological problems such as depression and irritability. 

Vitamin B12 is stored in the liver, which explains why deficiencies can take as long as 2-4 years to develop and symptoms to manifest.

Deficiencies tend to be due to one of three courses; malabsorption, insufficient intake or medical conditions.

You may want to test for vitamin B12 deficiency if you have any of the following:

The most common cause of B12 deficiency. This condition affects the stomach’s and ability to absorb B12 and is more common in females over 50 years of age and those with autoimmune conditions.

Vitamin B12 is found almost exclusively in animal products with the exception of small amount in some types of algae, which means that a strict vegan diets can lead to deficiencies.

The Vegan Society recommends B12 supplements daily providing at least 10mcg, OR a weekly B12 supplement providing at least 2,000 mcg. It is also advisable for vegans to include fortified cereals and fortified dairy-free milks in their diet.

Vegetarian diets are slightly less susceptible to deficiencies as long as they are including dairy products and some fortified foods within their diet.

Vitamin B12 deficiencies appear to be more common in older adults with it affecting around 1 in 10 people aged 75 or over, and 1 in 20 people aged 65 to 74 [3].

This can boil down to the fact older adults are more susceptible to conditions that reduce levels of stomach acid, which is an essential component for B12 absorption.

Older adults may want to think about increasing intake of fortified foods such as cereals or supplementation as these forms of B12 require less stomach acid for absorption.

Metformin is most commonly taken for diabetes and insulin resistances and has been shown to reduce B12 levels by 30% for people who take metformin chronically [4].

Proton pump inhibitors (PPIs) are prescribed medicines commonly used to treat acid reflux and indigestion. These inhibit the production of stomach acid, which negatively affects vitamin B12 absorption from the food we eat.

Other conditions that may lead to deficiencies:

• Gastritis and Pylori infections
• Coeliac disease
• Gastric bypass
• Excess alcohol consumption or heavy drinkers
• SIBO 

A blood test will measure B12 levels circulating in the bloodstream. 

The Department of Health recommends that you do not exceed 2000mcg or 2mg per day in supplement form.

B12 injections are being marketed online and on the high street, with numerous spas offering the service and even Wowcher deals! Many of these injections come with health claims such as ‘weight loss’, ‘quick burst of energy’, ‘hangover cure’ and ‘helps you get up in the morning!’

The truth is, that unless you have a vitamin B12 deficiency, there is no evidence to support these health claims. The B12 dose given with injections are usually many times the level the body can absorb, so most of the B12 is rapidly excreted in the urine.. #expensiveurine!

In the UK, B12 injections can only be used as a medical treatment when under prescription, otherwise it’s against the law for companies to claim it can relieve symptoms, provide cures or remedies. At the end of the day, it is important to be wary of any company making ‘to-good-to-be-true’ claims, and if you have concerns about deficiencies it is important to visit your GP to get your levels checked.

1. Hunt, A., Harrington, D. and Robinson, S. (2014). Vitamin B12 deficiency. BMJ, 349(sep04 1), pp.g5226-g5226.
2. Sukumar, N., Adaikalakoteswari, A., Venkataraman, H., Maheswaran, H. and Saravanan, P. (2016). Vitamin B12 status in women of childbearing age in the UK and its relationship with national nutrient intake guidelines: results from two National Diet and Nutrition Surveys. BMJ Open, 6(8), pp.e011247.
3. nhs.uk (2017). Vitamin B12 or folate deficiency anaemia - NHS Choices. [online] available at: 
http://www.nhs.uk/Conditions/Anaemia-vitamin-B12-and-folate-deficiency/Pages/Introduction.aspx [Accessed 6 Oct. 2017].
4.  Gilligan, M. (2002). Metformin and Vitamin B12 Deficiency. Archives of Internal Medicine, 162(4), pp.484-485